Health & Environmental Research Online (HERO)


Print Feedback Export to File
5083675 
Journal Article 
Health status of elderly people living near e-waste recycling sites: association of e-waste dismantling activities with legacy perfluoroalkyl substances (PFASs) 
Zhang, T; Zhang, B; Bai, X; Yao, Y; Wang, L; Shu, Y; Kannan, K; Huang, X; Sun, H 
2019 
Yes 
Environmental Science & Technology Letters
EISSN: 2328-8930 
133-140 
English 
The elderly people living near electronic waste (e-waste) dismantling sites are susceptible to elevated chemical exposure, which is acerbated by hypometabolism and diminished immune tolerance. In this study, paired serum and urine samples collected from 1025 elderly people (≥60 years old) living near e-waste dismantling sites (n = 800) and reference areas (n = 225) in South China were analyzed for markers of health status and chemical exposures. Our results indicated that among all the health indicators fasting blood glucose (FBG) and urinary clinical markers were significantly higher in e-waste areas than in the reference area. Sixteen legacy perfluoroalkyl substances (PFASs) were determined in serum samples of elderly individuals living near e-waste dismantling areas (n = 171) and a reference area (n = 50). Serum PFASs concentrations in individuals from e-waste dismantling areas were significantly higher (p < 0.05) than those from the reference area, which indicated that e-waste dismantling activities are a source of exposure to PFASs. Association between PFASs exposure and personal health history showed that body mass index (BMI) was significantly positively (p < 0.05) associated with serum PFHxA, PFHpA, PFOA, and PFNA concentrations. Negative associations between FBG and serum PFUnDA (r = −0.160, p < 0.05) and PFTeDA (r = −0.157, p < 0.05) were also found. Our results suggest that PFASs exposure is associated with adverse health outcomes in elderly population living around e-waste dismantling sites. 
article; blood glucose; blood serum; body mass index; elderly; electronic wastes; health status; immunosuppression; perfluorocarbons; perfluorooctanoic acid; recycling 
IRIS
• PCBs
     Excluded
     Litsearches
          Litsearch: Aug 2018 - Aug 2019
               WoS
PFAS
• Additional PFAS (formerly XAgency)
• PFAS 150
     Literature Search Update December 2020
          WOS
     Literature Search August 2019
          Web of Science
     Screened Studies
          Included
               Include (TIAB)
               Include (Full Text)
     Perfluorinated compounds
     Perfluoroheptanoic acid
     Perfluorononanoic acid
     Perfluorotetradecanoic acid
     Perfluoroundecanoic acid
• PFAS Universe
     Data Source
          Web of Science
          Screened Studies
               Included
                    Include (TIAB)
               Excluded
                    Exclude (Full Text)
     Perfluoroheptanoate
     Perfluoroheptanoic acid
     Perfluorohexadecanoic acid
     Perfluorooctanoate
     Perfluorotetradecanoate
     Perfluorotetradecanoic acid
     Perfluoroundecanoate
     Perfluoroundecanoic acid
     Perfluorooctanoic acid
• PFDA
     Literature Searches (through April 2023 update and post-public comment/peer review)
          Title & Abstract Screening
               Full Text Screening
                    Studies Meeting PECO
                         Human health effects studies
• PFHxA
     Scopus: April 2021
     Title and Abstract Screening
          Full Text Screening
               Studies Meeting PECO
                    Human health effects studies
     HAWC
• PFHxS
     Database searches
          Other
     Inclusion
          Full Text
               Human Study
• PFNA
     Literature Search
          WOS
     PFNA May 2019 Update
          Web of Science
     LitSearch: May 2019 - May 2020
          WoS
     Title and Abstract Screening
          Full Text Screening
               Studies Meeting PECO
                    Human health effects studies
OW - HHRAB
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search Update (2013-2019)
          WOS