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5370813 
Journal Article 
Spectrophotometric estimation of propranolol in tablet dosage form 
Bhandari, A; Kumar, B; Patel, R 
2008 
Yes 
Asian Journal of Chemistry
ISSN: 0970-7077
EISSN: 0975-427X 
ASIAN JOURNAL OF CHEMISTRY 
SAHIBABAD 
20 
1 
802-804 
English 
WOS:000259602100119 
A simple and accurate spectrophotometric method has been developed for the quantitative estimation of propranolol in bulk and tablets. The method is based on the reaction of propranolol with 1-chloro-2,4-dinitrobenzene, forming a complex, which is analyzed by spectrophotometry. The absorbance maxima (λmax) was found to be 314.6 nm. Optimization of reaction was carried out with the factors, temperature, time, stability of complex, molar ratio of drug: reagent. The proposed method was validated as per ICH guidelines. 
propranolol; spectrophotometry; 1-chloro-2,4-dinitrobenzene 
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