Toxicological review of Ethylene glycol monobutyl ether (EGBE) (CASRN 111-76-2) in support of summary information on the Integrated Risk Information System (IRIS).
U.S. Environmental Protection Agency, Integrated Risk Information System
The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to ethylene glycol monobutyl ether (EGBE). It is not intended to be a comprehensive treatise on the chemical or toxicological nature of EGBE. This document presents background information and justification for the Integrated Risk Information System (IRIS) Summary of the hazard and dose-response assessment of ethylene glycol monobutyl ether (EGBE). IRIS Summaries may include oral reference dose (RfD) and inhalation reference concentration (RfC) values for chronic and other exposure durations, and a carcinogenicity assessment.