[On the toxicity of various hydrocarbon vapors]
Lazarew, NW
| HERO ID | 631192 |
|---|---|
| In Press | No |
| Year | 1929 |
| Title | [On the toxicity of various hydrocarbon vapors] |
| Authors | Lazarew, NW |
| Journal | Archiv fuer Experimentelle Pathologie und Pharmakologie |
| Volume | 143 |
| Issue | 2 |
| Page Numbers | 223-233 |
| Abstract | The toxicity of 35 hydrocarbon vapors including paraffins, cycloparaffins, unsaturated hydrocarbons, and aromatic hydrocarbons was determined in mice. The paraffins included pentane, hexane (110543), heptane (142825), 2-methylhexane, octane (111659), 2,5-dimethylhexane, and 2,5-dimethyloctane. The aromatic hydrocarbons were the most toxic followed by the unsaturated hydrocarbons, cycloparaffins, and paraffins. The decrease in toxicity was found to be parallel to the decrease in water solubility. It could not be determined whether the low degree of toxicity of paraffin and cycloparaffin vapors were due to the low degree of toxicity of hydrocarbons themselves or mainly to their poor solubility. The low degree of toxicity of hydrocarbons is doubted. Intoxication by paraffin and cycloparaffin vapors are considered to initially stimulate the brain center; later, however, the latter weakens without the spinal cord weakening for a longer period of time. A tension cramp, part of the initial signs of toxicity, is considered due to a sudden weakening of the respiratory center, with sustained or even increased stimulation of the spinal cord. (German; English translation available) |
| Doi | 10.1007/BF01864847 |
| Url | http://www.springerlink.com/index/10.1007/BF01864847 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | German |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>DCN-174843</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>TRANS</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Aliphatic hydrocarbons</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Toxic substances</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Chemical properties</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Nervous system disorders</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Organic solvents</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Alkanes</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Neurotoxins</kw> |
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