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Citation
Tags
HERO ID
631290
Reference Type
Journal Article
Title
A biochemical study on variability of superoxide dismutase, catalase and glutathione peroxidase in dry cleaners
Author(s)
Anbhazhagan, S; Winkins, SS
Year
2008
Is Peer Reviewed?
Yes
Journal
Indian Journal of Clinical Biochemistry
ISSN:
0970-1915
EISSN:
0974-0422
Book Title
Indian journal of clinical biochemistry : IJCB
Volume
23
Issue
2
Page Numbers
198-199
DOI
10.1007/s12291-008-0044-0
Abstract
Several chemicals which induce cytotoxicity are broadly classified into three types and they are organophosphate, organochlorine and carbomate compounds. Perchloroethylene has been clearly identified as a carcinogen in experimental animals and it's a very common carcinogen used for dry clean purpose. Hence, in the present study, blood samples from dry cleaners were taken, Superoxide dismutase, Catalase and Glutathione peroxidase activity was estimated in blood samples of dry cleaners. There was a significant increase in the activity of Catalase, Glutathione Peroxidase, Superoxide Dismutase in dry cleaners of chronically exposed to perchloroethylene as compared to controls. The increased activities of antioxidant enzymes may be a compensatory regulation in response to increased oxidative stress induced by perchloroethylene.
Keywords
Perchloroethylene; Antioxidant enzymes; Dry cleaners; Catalase; Glutathione Peroxidase; Superoxide Dismutase
Tags
IRIS
•
Tetrachloroethylene (Perc) (Final, 2012)
All References
Exposure
•
Trichloroethylene (TCE) (Final, 2011)
OPPT REs
•
OPPT_N-methylpyrrolidone (NMP)_F. Human Health
Total – title/abstract screening
On topic
Peer review
Primary source
•
OPPT_Perchloroethylene (Perc)_F. Human Health
Total – title/abstract screening
On topic
Peer review
Primary source
Cited in IRIS document or IRIS HERO page
On topic - additional tags for titles/abstracts
MOA
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