Health & Environmental Research Online (HERO)


Print Feedback Export to File
631290 
Journal Article 
A biochemical study on variability of superoxide dismutase, catalase and glutathione peroxidase in dry cleaners 
Anbhazhagan, S; Winkins, SS 
2008 
Yes 
Indian Journal of Clinical Biochemistry
ISSN: 0970-1915
EISSN: 0974-0422 
Indian journal of clinical biochemistry : IJCB 
23 
198-199 
Several chemicals which induce cytotoxicity are broadly classified into three types and they are organophosphate, organochlorine and carbomate compounds. Perchloroethylene has been clearly identified as a carcinogen in experimental animals and it's a very common carcinogen used for dry clean purpose. Hence, in the present study, blood samples from dry cleaners were taken, Superoxide dismutase, Catalase and Glutathione peroxidase activity was estimated in blood samples of dry cleaners. There was a significant increase in the activity of Catalase, Glutathione Peroxidase, Superoxide Dismutase in dry cleaners of chronically exposed to perchloroethylene as compared to controls. The increased activities of antioxidant enzymes may be a compensatory regulation in response to increased oxidative stress induced by perchloroethylene. 
Perchloroethylene; Antioxidant enzymes; Dry cleaners; Catalase; Glutathione Peroxidase; Superoxide Dismutase 
IRIS
• Tetrachloroethylene (Perc) (Final, 2012)
     All References
     Exposure
• Trichloroethylene (TCE) (Final, 2011)
OPPT REs
• OPPT_N-methylpyrrolidone (NMP)_F. Human Health
     Total – title/abstract screening
          On topic
               Peer review
                    Primary source
• OPPT_Perchloroethylene (Perc)_F. Human Health
     Total – title/abstract screening
          On topic
               Peer review
                    Primary source
               Cited in IRIS document or IRIS HERO page
     On topic - additional tags for titles/abstracts
          MOA