US EPA

6575094 

Journal Article 

Anxiety Symptoms Differ in Youth With and Without Tic Disorders 

Vermilion, J; Pedraza, C; Augustine, EF; Adams, HR; Vierhile, A; Lewin, AB; Collins, AT; Mcdermott, MP; O'Connor, T; Kurlan, R; van Wijngaarden, E; Murphy, TK; Mink, JW; , 

2020 

Yes 

Child Psychiatry and Human Development
ISSN: 0009-398X
EISSN: 1573-3327 

52 

2 

301-310 

English 

32519083 

10.1007/s10578-020-01012-6 

We compared anxiety symptoms in youth with and without tic disorders by comparing scores on the Multidimensional Anxiety Scale for Children (MASC) in youth with tic disorders to those in a concurrent community control group and in a group of treatment-seeking anxious youth from the Child/Adolescent Anxiety Multimodal Study (CAMS). Data from 176 youth with tic disorders, 93 control subjects, and 488 CAMS participants were included. Compared to youth with tic disorders, controls had lower total MASC scores (p < 0.0001) and CAMS participants had similar total MASC scores (p = 0.13). Separation Anxiety (p = 0.0003) and Physical Symptom (p < 0.0001) subscale scores were higher in youth with tic disorders than in CAMS participants. We conclude that the anxiety symptom profile differs in youth with and without tic disorders, which may have important implications for targeting treatment of anxiety in youth with tic disorders.