Maitake D-fraction: Healing and preventive potential for cancer
Nanba, H
| HERO ID | 7334015 |
|---|---|
| In Press | No |
| Year | 1997 |
| Title | Maitake D-fraction: Healing and preventive potential for cancer |
| Authors | Nanba, H |
| Journal | Journal of Orthomolecular Medicine |
| Volume | 12 |
| Issue | 1 |
| Page Numbers | 43-49 |
| Abstract | I have been studying medicinal mushrooms for the last 15 years and have reported that of all mushrooms studied, Maitake Mushroom (Grifola frondosa) has the strongest activity in tumor growth inhibition both administered orally and intraperitoneally. In this report, Maitake extract D-fraction was investigated to determine its effectiveness not only on the inhibition against tumors already growing, but also on the inhibition of formation of the secondary focus due to metastasis of tumor cells in lymph and/or blood. In the tests of cancer inhibition rates on mice bearing MM46 (breast cancer), they were bred for one month with foods containing 20% edible mushroom powder. The result was that Maitake outperformed all other mushrooms. Through the 31 day oral administration, total remission of the tumor was visibly confirmed on four out of ten Maitake fed mice. The remaining six rodents also indicated almost 90% suppression rate compared to untreated (control) mice. Most other mushroom extracts are reported ineffective when given orally. The results of human studies on Maitake D-fraction is reported which indicated strong potential of Maitake D-fraction for cancer treatment. |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031001457&partnerID=40&md5=5888b371dc2da545923d7281c2a247ce |
| Is Public | Yes |
| Language Text | English |
| Keyword | cisplatin; cyclophosphamide; doxorubicin; etoposide; fluorouracil; lomustine; mitomycin c; adult; aged; animal experiment; animal model; antineoplastic activity; article; astrocytoma; breast cancer; cancer prevention; clinical article; female; human; intraperitoneal drug administration; liver cancer; lung cancer; male; metastasis; mouse; mushroom; nonhuman; oral drug administration |