Chemoselective cleavage of benzyl ethers, esters, and carbamates in the presence of other easily reducible groups | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7584998

Reference Type

Journal Article

Title

Chemoselective cleavage of benzyl ethers, esters, and carbamates in the presence of other easily reducible groups

Author(s)

Coleman, RS; Shah, JA

Year

1999

Is Peer Reviewed?

Journal

Synthesis
ISSN: 0039-7881
EISSN: 1437-210X

Issue

SPEC. ISS.

Page Numbers

1399-1400

Language

English

Abstract

Mild experimental conditions are reported that permit the selective cleavage of benzyl protecting groups in the presence of other easily reduced groups such as aryl chlorides and bromides, cyclopropanes, and alkenes, using triethylsilane and palladium chloride.

Keywords

Benzyl group; Deprotection; Hydrogenolysis; Protecting group; benzyl carbamate; benzyl derivative; benzyl ester; benzyl ether; unclassified drug; article; chemical reaction; hydrogenation; reduction; synthesis