REAGENTS FOR SPECIFIC MODIFICATION OF BIOPOLYMERS .5. SYNTHESIS OF 1-AMINO-3-[4-(N-2-CHLOROETHYL-N-METHYLAMINO)PHENYL]PROPANE
Gall, AA; Ivanova, TM; Shishkin, GV; ,
| HERO ID | 7655972 |
|---|---|
| In Press | No |
| Year | 1991 |
| Title | REAGENTS FOR SPECIFIC MODIFICATION OF BIOPOLYMERS .5. SYNTHESIS OF 1-AMINO-3-[4-(N-2-CHLOROETHYL-N-METHYLAMINO)PHENYL]PROPANE |
| Authors | Gall, AA; Ivanova, TM; Shishkin, GV; , |
| Page Numbers | 27-31 |
| Abstract | 1-Amino-3-[4-(N-2-chlorethyl-N-methylamino)phenyl]propane was obtained from N-2-chloroethyl-N-methylaniline according to the scheme, including vinylformylation by Jutz, a reaction with hydroxylamine and simultaneous hydrogenation of the oxime group and the ethylenic bond. The method of synthesis of 4(N-2-chloroethyl-N-methylamino)benzylamine was improved while adjusting the conditions of hydrogenation. The synthesized reagent is used for specific modification of nucleic acids. |
| Wosid | WOS:A1991HE43300004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: SIBIRSKII KHIMICHESKII ZHURNAL 0134-2428 |
| Is Public | Yes |