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7742802 
Journal Article 
Glow discharge modified tissue culture polystyrene: role of surface chemistry in cellular attachment and proliferation 
Mitchell, SA; Davidson, MR; Bradley, RH 
2006 
1 
Surface Engineering
ISSN: 0267-0844
EISSN: 1743-2944 
MANEY PUBLISHING 
LEEDS 
22 
5 
337-344 
English 
WOS:000241671100004 
A radio frequency glow discharge has been used to selectively deposit non-polar hydrocarbon films onto tissue culture grade polystyrene surfaces. The resulting surfaces have been studied using X-ray photoelectron spectroscopy, contact angle analysis and atomic force microscopy. Regions with differing surface chemistry and polarity have been produced on the same substrate using a simple masking technique and allowed the spatially controlled attachment of mammalian cells. The attachment of cells to plasma modified tissue culture polystyrene surfaces has been correlated to the concentration of specific oxygen functional groups. © 2006 Institute of Miterials, Minerals and Mining. 
plasma polymerisation; n-hexane; cell culture; XPS; AFM; advancing water contact angle; surface patterning; spatial control of cells