A new Co2(CO)8-mediated tandem [5 + 1]/[2 + 2 + 1]-cycloaddition reaction: A one-pot synthesis of tricyclic δ-lactones from cis-epoxy ene-ynes | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

8716846

Reference Type

Journal Article

Title

A new Co2(CO)8-mediated tandem [5 + 1]/[2 + 2 + 1]-cycloaddition reaction: A one-pot synthesis of tricyclic δ-lactones from cis-epoxy ene-ynes

Author(s)

Odedra, A; Wu, CJ; Madhushaw, RJ; Wang, SL; Liu, RS

Year

2003

Is Peer Reviewed?

Yes

Journal

Journal of the American Chemical Society
ISSN: 0002-7863
EISSN: 1520-5126

Volume

125

Issue

Page Numbers

9610-9611

Language

English

DOI

10.1021/ja0346633

Abstract

In the presence of Co2(CO)8 and CO, cis-epoxyalkynes bearing a tether olefin undergo a tandem [5 + 1]/[2 + 2 + 1]-cycloaddition to give tricyclic δ-lactones efficiently in a one-pot operation. The reaction mechanism is proposed to involve a cobalt-coordinated cyclic allene species. Copyright 2003 American Chemical Society.