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95518 
Journal Article 
Mutagenicity of industrial compounds: styrene and its possible metabolite styrene oxide 
Loprieno, N; Abbondandolo, A; Barale, R; Baroncelli, S; Bonatti, S; Bronzetti, G; Cammellini, A; Corsi, C; Corti, G; Frezza, D; Leporini, C; Mazzaccaro, A; Nieri, R; Rosellini, D; Rossi, AM 
1976 
1 
Mutation Research
ISSN: 0027-5107
EISSN: 1873-135X 
40 
4 
317-324 
English 
796697 
WOS:A1976CM88100005 
Summary Styrene and its presumed metabolite, styrene oxide, were tested for their mutagenic effect on a forward mutation system of yeast and of Chinese hamster cells, and on a gene-conversion system of yeast. Experiments with liver microsomal preparations and host-mediated assay with yeast were also carried out. Styrene oxide was mutagenic in all test systems. Styrene was mutagenic only in the host-mediated assay.