OPPT_1,4-Dioxane_A. Summary

Project ID

2515

Category

OPPT REs

Added on

June 9, 2016, 11:40 a.m.

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162 items found. Displaying 25 items on page 1 of 7.

Technical Report

Toxicological review of 1,4-Dioxane (CAS No. 123-91-1) in support of summary information on the Integrated Risk Information System (IRIS)

U.S. Environmental Protection Agency 2010

Abstract  This document presents background information and justification for the Integrated Risk Information System (IRIS) Summary of the hazard and dose-response assessment of 1,4-dioxane. IRIS Summaries may include oral reference dose (RfD) and inhalation reference concentration (RfC) values for chronic and subchronic exposure durations, and a carcinogenicity assessment.

Book/Book Chapter

Dioxane

[No authors listed] 2001
DOI
Book/Book Chapter

Sax's dangerous properties of industrial materials

Lewis RJ Sr 2012

Abstract  Since its inception in the early 1950's, this book has become the "bible" for those who need to evaluate the hazard of substances used in commerce. The book contains extensive data on approximately 28,000 substances. It is designed to fill the information needs of professionals who must work with and evaluate the hazards of chemicals.

Book/Book Chapter

Tetrabromobisphenol A

O'Neil, MJ 2013
PubMed
DOI
Journal Article

The Development of the EASE Model

Tickner J et al. 2005

Abstract  The estimation and assessment of substance exposure (EASE) model has been under development and in use since the early 1990s. It is a general model that can be used to predict workplace exposure to any substance hazardous to health. The current EASE model (version 2.0) has been used widely in the risk assessment of new and existing chemicals by the UK Health and Safety Executive (HSE) and other regulatory agencies. EASE has also been distributed globally to over 200 users and therefore may have been used for many other purposes. Despite widespread use of the model, neither the development of its structure nor its underlying concepts and principles have been published in the open literature. Using surviving documentary evidence and discussions with key personnel, the creation and development of the model from 1992 to 2002 is described. The role of the HSE's National Exposure Database (NEDB) as the principal data source for the development of the model output exposure ranges is described. A number of problems and limitations of the model have been identified and the description of the model's development provides some explanation of their presence.

Technical Report

Guidelines for carcinogen risk assessment

U.S. Environmental Protection Agency 2005

Abstract  These guidelines revise and replace the U.S. Environmental Protection Agency’s (EPA’s, or the Agency’s) Guidelines for Carcinogen Risk Assessment, published in 51 FR 33992, September 24, 1986 (U.S. EPA, 1986a) and the 1999 interim final guidelines (U.S. EPA, 1999a; see U.S. EPA 2001b). They provide EPA staff with guidance for developing and using risk assessments. They also provide basic information to the public about the Agency's risk assessment methods.

Technical Report

Report on carcinogens, 14th edition: Glycidol

National Toxicology Program 2011

Abstract  Glycidol is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

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