PFHxA

Project ID

2628

Category

PFAS

Added on

Aug. 10, 2017, 6:31 a.m.

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23 items found.

Archival Material

Study information: CEBS accession number 002-02654-0001-0000-0: Perfluorohexanoic acid (PFHXA)

National Toxicology Program 2005

Abstract  CEBS Accession Number: 002-02654-0001-0000-0 Chemical Name: Perfluorohexanoic acid (PFHXA) CASRN: 307-24-4 NTP Study Type: Genetic Toxicology - Bacterial Mutagenicity NTP Study ID: A97455 Vehicle Control: Dimethyl Sulfoxide Study Result: Negative

PubMed
DOI WoS
Journal Article

The pKa values of PFOA and other highly fluorinated carboxylic acids

Goss KU 2008

Abstract  The dissociated and nondissociated species of any organic acid differ largely in their physicochemical behavior. The ratio of both species in aqueous systems is determined by the respective pKa value. For perfluorooctanoic acid recent fate-modeling studies have applied a pKa value of 2.8. This value likely is too high by 3 log units. Here, the correct value is estimated to be close to -0.5 based on analogy considerations and molecular modeling. Calculated pKa values for other highly fluorinated carboxylic acids are also presented.

Archival Material

28-day evaluation of the toxicity (C20613) of perfluorohexanoic acid (PFHxA) (307-24-4) on Harlan Sprague-Dawley rats exposed via gavage

National Toxicology Program 2018

Abstract  On 05 April 2018 indirect bilirubin measurements were added to the clinical chemistry tables. No changes were made to existing data.

DOI
Journal Article

Ambient temperature vapor pressure and adsorption capacity for (perfluorooctyl) ethylene, 3-(perfluorobutyl)propanol, perfluorohexanoic acid, ethyl perfluorooctanoate, and perfluoro-3,6-dioxaheptanoic acid

Schindler BJ et al. 2013

Abstract  With increased use of highly fluorinated compounds has come an increased need for knowledge of the fundamental properties of these chemicals, such as vapor pressure, to determine how they will behave in the environment and how to remove them. A modified vapor saturation method was used to measure the ambient temperature vapor pressure of 3-(perfluorobutyl)propanol, (perfluorooctyl)ethylene, perfluorohexanoic acid, ethyl perfluorooctanoate, and perfluoro-3,6-dioxaheptanoic acid between (254.15 and 309.15) K. The freezing point for perfluorohexanoic acid was determined to be between (291.15 and 293.15) K The vapor pressures, which ranged from (0.87 to 978) Pa, were used to generate saturated vapor streams of the compound so that adsorption capacities on BPL activated carbon could be determined. Adsorption equilibrium data for three of the chemicals, measured at a feed concentration of 139 mu L.L-1 at high and low relative humidity, are presented and discussed.

Archival Material

Study information: CEBS accession number 002-02654-0002-0000-1: Perfluorohexanoic acid (PFHXA)

National Toxicology Program 2012

Abstract  CEBS Accession Number: 002-02654-0002-0000-1 Chemical Name: Perfluorohexanoic acid (PFHXA) CASRN: 307-24-4 NTP Study Type: Genetic Toxicology - Micronucleus NTP Study ID: G04048 Strain and Species: Harlan Sprague Dawley Rat Study Result: Male: Equivocal; Female: Negative

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