Abstract  Aliphatic, linear dicarboxylic acids and branched dicarboxylic acids are the subject of this article. These dibasic acids are referred to by their trivial names, IUPAC system or by adding the suffix “dicarboxylic acid“ to the name of the hydrocarbon skeleton. For example a 10‐carbon atom dibasic acid is designated sebacic acid, decanoic or 1,8‐octane‐dicarboxylic acid. Physical and chemical properties of the most common dibasic acids are discussed. Manufacture and uses for glutaric acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, dodecanoic acid, brassylic acid and C‐19, C‐20, and C‐22 dicarboxylic acids are given. These diacids are intermediates for the manufacture of diesters, polyesters, and polyamides. These derivatives have many applications ,eg, as plasticizing agents, lubricants, heat‐transfer fuids, inks and coatings, insecticides. Azaleic acid is used in acne preparations. Toxicities and environmental concerns are also discussed.

Abstract  Caprylyl glycol and related 1,2-glycols are used mostly as skin and hair conditioning agents and viscosity agents in cosmetic products, and caprylyl glycol and pentylene glycol also function as cosmetic preservatives. The Cosmetic Ingredient Review (CIR) Expert Panel noted that, while these ingredients are dermally absorbed, modeling data predicted decreased skin penetration of longer chain 1,2-glycols. Because the negative oral toxicity data on shorter chain 1,2-glycols and genotoxicity data support the safety of the 1,2-glycols reviewed in this safety assessment, the Panel concluded that these ingredients are safe in the present practices of use and concentration described in this safety assessment.