Alcohol-water as a novel medium for beta-hematin preparation

Blauer, G; Akkawi, M

HERO ID

1037520

Reference Type

Journal Article

Year

2002

Language

English

PMID

11811943

HERO ID 1037520
In Press No
Year 2002
Title Alcohol-water as a novel medium for beta-hematin preparation
Authors Blauer, G; Akkawi, M
Journal Archives of Biochemistry and Biophysics
Volume 398
Issue 1
Page Numbers 7-11
Abstract It is shown that alcohol-water mixtures (e.g., 43 wt% ethanol) provide a suitable medium for the efficient production in high yield of beta-hematin from ferriprotoporphyrin IX (FP), as measured by infrared spectroscopy. Previous and present light-absorption data of FP, obtained under specific acid conditions in an ethanol-water medium, suggest the presence of FP monomers, which are considered to promote the reaction leading to beta-hematin. Other aspects of the mechanism of reaction are discussed.
Doi 10.1006/abbi.2001.2638
Pmid 11811943
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Dupe Override No
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Language Text English
Is Qa No