Integrating uncertainty and interindividual variability in environmental risk assessment
Bogen, KT; Spear, RC
HERO ID
1060481
Reference Type
Journal Article
Year
1987
Language
English
PMID
| HERO ID | 1060481 |
|---|---|
| In Press | No |
| Year | 1987 |
| Title | Integrating uncertainty and interindividual variability in environmental risk assessment |
| Authors | Bogen, KT; Spear, RC |
| Journal | Risk Analysis |
| Volume | 7 |
| Issue | 4 |
| Page Numbers | 427-436 |
| Abstract | An integrated, quantitative approach to incorporating both uncertainty and interindividual variability into risk prediction models is described. Individual risk R is treated as a variable distributed in both an uncertainty dimension and a variability dimension, whereas population risk I (the number of additional cases caused by R) is purely uncertain. I is shown to follow a compound Poisson-binomial distribution, which in low-level risk contexts can often be approximated well by a corresponding compound Poisson distribution. The proposed analytic framework is illustrated with an application to cancer risk assessment for a California population exposed to 1,2-dibromo-3-chloropropane from ground water. |
| Doi | 10.1111/j.1539-6924.1987.tb00480.x |
| Pmid | 3444930 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |