Use of Monte Carlo simulation to investigate uncertainty in exposure modeling

Semple, SE; Proud, LA; Cherrie, JW

HERO ID

1060520

Reference Type

Journal Article

Year

2003

Language

English

PMID

14584515

HERO ID 1060520
In Press No
Year 2003
Title Use of Monte Carlo simulation to investigate uncertainty in exposure modeling
Authors Semple, SE; Proud, LA; Cherrie, JW
Journal Scandinavian Journal of Work, Environment and Health
Volume 29
Issue 5
Page Numbers 347-353
Abstract <strong>OBJECTIVES: </strong>This study used Monte Carlo (MC) simulation to examine the influence of uncertainty on an exposure model and to determine whether a difference exists between two worker groups in a ceramic fiber manufacturing plant.<br /><br /><strong>METHODS: </strong>Data on work practices and conditions were gathered in interviews with long-serving employees. With the use of previously developed deterministic modeling techniques and likely distributions for model parameters, MC simulations generated exposure profiles for the two job titles.<br /><br /><strong>RESULTS: </strong>The exposure profiles overlapped considerably, although the average estimated exposure for one job was approximately double that of the other. However, when the correlation between the model parameters in the two jobs was considered, it was concluded that there was a significant difference in the two estimates.<br /><br /><strong>CONCLUSIONS: </strong>Models are increasingly being used to estimate exposure. Different work situations inevitably result in different exposure estimates. However, it is difficult to determine whether such differences in estimated exposure between worker groups are simply the result of uncertainty with respect to the model parameters or whether they reflect real differences between occupational groups. This study demonstrates the value of MC simulation in helping define the uncertainty in deterministic model estimates.
Doi 10.5271/sjweh.741
Pmid 14584515
Wosid WOS:000186016900004
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword epidemiology; exposure assessment