Toxicology of cyclotrimethylenetrinitramine (RDX): Distribution and metabolism in the rat and the miniature swine

Schneider, NR; Bradley, SL; Andersen, ME

HERO ID

1065808

Reference Type

Technical Report

Year

1976

HERO ID 1065808
Year 1976
Title Toxicology of cyclotrimethylenetrinitramine (RDX): Distribution and metabolism in the rat and the miniature swine
Authors Schneider, NR; Bradley, SL; Andersen, ME
Publisher Text Armed Forces Radiobiology Research Institute
City Bethesda, MD
Page Numbers 28
Abstract Cyclotrimethylenetrinitramine (RDX) is an explosive extensively used by the military. It has caused convulsions in military field personnel ingesting it and in munition workers inhaling its dust during manufacture. At least one fatality was attributed to RDX toxicity in an European munitions manufacturing plant. In this country, RDX has been dumped into open pits for disposal after demilitarization, and in some instances has contaminated surface and ground water. It is possible that humans might be exposed to RDX in potable water. This study, initiated at the request of the Naval Medical Research and Development Command, was intended to determine the distribution, metabolism and excretion of RDX in laboratory animals and to estimate by inference the potential hazard to humans from RDX exposure.
Report Number AFRRI-SR76-34. ADA026892. CPIAC-1977-0686
Ntis Number ADA026892
Url https://ntrl.ntis.gov/NTRL/dashboard/searchResults.xhtml?searchQuery=ADA026892
Is Certified Translation No
Dupe Override No
Comments Journal: ISSN:
Is Public Yes
Keyword explosives, rdx, toxicology, military personnel, hazards, rats, humans, toxicity, metabolism, drinking water, water pollution, dosage, munitions industry, public health, dose rate, bioassay, laboratory animals, swine, excretion; Potable water, Environmental health