Probabilistic risk assessment of metals, acrylamide and ochratoxin A in instant coffee from Brazil, Colombia, Mexico and Peru
Guadalupe, GA; Grandez-Yoplac, DE; Arellanos, E; Doménech, E
| HERO ID | 12033137 |
|---|---|
| In Press | No |
| Year | 2024 |
| Title | Probabilistic risk assessment of metals, acrylamide and ochratoxin A in instant coffee from Brazil, Colombia, Mexico and Peru |
| Authors | Guadalupe, GA; Grandez-Yoplac, DE; Arellanos, E; Doménech, E |
| Journal | Foods |
| Volume | 13 |
| Issue | 5 |
| Abstract | This study analysed the probabilistic risk to consumers associated with the presence of iAs, Cd, Cr, Hg, Pb, acrylamide (AA) and ochratoxin A (OTA) in instant coffee from Brazil, Colombia, Mexico and Peru. The results found iAs to be the metal with the highest concentrations (3.50 x 10(-2) to 6.00 x 10(-2) mg/kg), closely followed by Pb (1.70 x 10(-2) to 2.70 x 10(-2) mg/kg) and Cr (5.00 x 10(-3) to 1.00 x 10(-2) mg/kg), although these differences were not significant between countries. Cd and Hg were not detected. Focusing on AA, the concentrations ranged from 1.77 x 10(-1) mg/kg (Peru) to 4.77 x 10(-1) mg/kg (Brazil), while OTA ranged from 1.32 x 10(-3) (Peru) to 1.77 x 10(-3) mg/kg (Brazil) with significant differences between countries in both cases. As regards risk, the hazard quotient and hazard index were less than 1, meaning that the consumption of instant coffee represents a low level of concern for non-genotoxic effects. The results of the combination of margin of exposure and probability of exceedance indicated that the non-genotoxic effects of Pb, AA and OTA pose no threat. However, the probability values of suffering cancer from iAs and AA (between 1 x 10(-6) and 1 x 10(-4)) indicated a moderate risk and that management measures should be taken. |
| Doi | 10.3390/foods13050726 |
| Pmid | 38472839 |
| Wosid | WOS:001182761900001 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | chemical analysis; consumer health; genotoxic and non-genotoxic effects; risk characterisation |