Community exposure to perfluorooctanoate: relationships between serum concentrations and exposure sources

Emmett, EA; Shofer, FS; Zhang, H; Freeman, D; Desai, C; Shaw, LM

HERO ID

1289798

Reference Type

Journal Article

Year

2006

Language

English

PMID

16902368

HERO ID 1289798
In Press No
Year 2006
Title Community exposure to perfluorooctanoate: relationships between serum concentrations and exposure sources
Authors Emmett, EA; Shofer, FS; Zhang, H; Freeman, D; Desai, C; Shaw, LM
Journal Journal of Occupational and Environmental Medicine
Volume 48
Issue 8
Page Numbers 759-770
Abstract <strong>OBJECTIVE: </strong>The objective of this study was to determine serum (perfluorooctanoate [PFOA]) in residents near a fluoropolymer production facility: the contributions from air, water, and occupational exposures, personal and dietary habits, and relationships to age and gender.<br /><br /><strong>METHODS: </strong>The authors conducted questionnaire and serum PFOA measurements in a stratified random sample and volunteers residing in locations with the same residential water supply but with higher and lower potential air PFOA exposure.<br /><br /><strong>RESULTS: </strong>Serum (PFOA) greatly exceeded general population medians. Occupational exposure from production processes using PFOA and residential water had additive effects; no other occupations contributed. Serum (PFOA) depended on the source of residential drinking water, and not potential air exposure. For public water users, the best-fit model included age, tap water drinks per day, servings of home-grown fruit and vegetables, and carbon filter use.<br /><br /><strong>CONCLUSIONS: </strong>Residential water source was the primary determinant of serum (PFOA).
Doi 10.1097/01.jom.0000232486.07658.74
Pmid 16902368
Wosid WOS:000239706700004
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Human exposure; Health hazards; Chemicals; Water supply; Hazardous substances; Water pollution
Is Qa No