Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: a review of rodent and human data
Rasier, G; Toppari, J; Parent, AS; Bourguignon, JP
HERO ID
1414747
Reference Type
Journal Article
Subtype
Review
Year
2006
Language
English
PMID
| HERO ID | 1414747 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2006 |
| Title | Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: a review of rodent and human data |
| Authors | Rasier, G; Toppari, J; Parent, AS; Bourguignon, JP |
| Journal | Molecular and Cellular Endocrinology |
| Volume | 254-255 |
| Page Numbers | 187-201 |
| Abstract | Natural hormones and some synthetic chemicals spread into our surrounding environment share the capacity to interact with hormone action and metabolism. Exposure to such compounds can cause a variety of developmental and reproductive detrimental abnormalities in wildlife species and, potentially, in human. Many experimental and epidemiological data have reported that exposure of the developing fetus or neonate to environmentally relevant concentrations of some among these endocrine disrupters induces morphological, biochemical and/or physiological disorders in brain and reproductive organs, by interfering with the hormone actions. The impact of such exposures on the hypothalamic-pituitary-gonadal axis and subsequent sexual maturation is the subject of the present review. We will highlight epidemiological human studies and the effects of early exposure during gestational, perinatal or postnatal life in female rodents. |
| Doi | 10.1016/j.mce.2006.04.002 |
| Pmid | 16720078 |
| Wosid | WOS:000239616900026 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000239616900026 |
| Is Public | Yes |
| Language Text | English |
| Keyword | female puberty; endocrine disrupters |