Enhancement of lung cancer by cigarette smoking in uranium and other miners

Archer, VE

HERO ID

1421091

Reference Type

Journal Article

Year

1985

Language

English

PMID

3986824

HERO ID 1421091
In Press No
Year 1985
Title Enhancement of lung cancer by cigarette smoking in uranium and other miners
Authors Archer, VE
Journal Carcinogenesis: A Comprehensive Survey
Volume 8
Issue ED.
Page Numbers 23-37
Abstract There are substantial animal and epidemiological data related to cigarette smoking and lung cancer among miners exposed to elevated levels of radon daughters that appears to be in disagreement. An hypothesis is advanced that explains most of this disagreement as being derived from temporal differences of cancer expression. The hypothesis is that a given radiation exposure induced a finite number of lung cancers, which have shorter latent periods due to the cancer promotion activity of smoke among cigarette smokers. According to this hypothesis, the life-shortening effect is greater among smoking miners than nonsmoking miners, and the ultimate number of lung cancers among smoking miners will be only a little larger than among nonsmokers. The greater number will derive from the additive effect of radiation and smoking, plus the greater force of competing causes of death among elderly nonsmokers.
Pmid 3986824
Is Certified Translation No
Dupe Override No
Comments Journal: MASS ISSN:
Is Public Yes
Language Text English
Keyword <?xml version="1.0" encoding="UTF-8"?><kw>DCN-154387</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Lung cancer</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Cigarette smoking</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Uranium miners</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Epidemiology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Laboratory animals</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Radiation exposure</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Carcinogenesis</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Ionizing radiation</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Humans</kw>
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