Update of the NIOSH Life Table Analysis System: A Person-Years Analysis Program for the Windows Computing Environment

Schubauer-Berigan, MK; Hein, MJ; Raudabaugh, WM; Ruder, AM; Silver, SR; Spaeth, S; Steenland, K; Petersen, MR; Waters, KM

HERO ID

1431279

Reference Type

Journal Article

Year

2011

Language

English

PMID

22068723

HERO ID 1431279
In Press No
Year 2011
Title Update of the NIOSH Life Table Analysis System: A Person-Years Analysis Program for the Windows Computing Environment
Authors Schubauer-Berigan, MK; Hein, MJ; Raudabaugh, WM; Ruder, AM; Silver, SR; Spaeth, S; Steenland, K; Petersen, MR; Waters, KM
Journal American Journal of Industrial Medicine
Volume 54
Issue 12
Page Numbers 915-924
Abstract Background Person-years analysis is a fundamental tool of occupational epidemiology. A life table analysis system (LTAS), previously developed by the National Institute for Occupational Safety and Health, was limited by its platform and analysis and reporting capabilities. We describe the updating of LTAS for the Windows operating system (LTAS. NET) with improved properties. <br> <br>Software Development Process A group of epidemiologists, programmers, and statisticians developed software, platform, and computing requirements. Statistical methods include the use of (indirectly) standardized mortality ratios, (directly) standardized rate ratios, confidence intervals, and P values based on the normal approximation and exact Poisson methods, and a trend estimator for linear exposure-response associations. <br> <br>Software Features We show examples using LTAS. NET to stratify and analyze multiple fixed and time-dependent variables. Data import, stratification, and reporting options are highly flexible. Users may export stratified data for Poisson regression modeling. <br> <br>Conclusions LTAS. NET incorporates improvements that will facilitate more complex person-years analysis of occupational cohort data. Am. J. Ind. Med. 54: 915-924, 2011. Published 2011. This article is a U. S. Government work and is in the public domain in the USA.
Doi 10.1002/ajim.20999
Pmid 22068723
Wosid WOS:000297414700004
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000297414700004
Is Public Yes
Language Text English
Keyword epidemiologic methods; cohort analysis; person-years analysis; occupational; statistical methods