Novel biflavone diglycosides and biological activity of Jatropha multifida leaves
Marzouk, MS; Moharram, FA; Haggag, EG; El-Batran, SM; Mahmoud, II; Ibrahim, RR
| HERO ID | 1450274 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Novel biflavone diglycosides and biological activity of Jatropha multifida leaves |
| Authors | Marzouk, MS; Moharram, FA; Haggag, EG; El-Batran, SM; Mahmoud, II; Ibrahim, RR |
| Journal | Chemistry of Natural Compounds |
| Volume | 48 |
| Issue | 5 |
| Page Numbers | 765-770 |
| Abstract | Chromatographic separation of the 80% aqueous methanol extract (AME) of Jatropha multifida Linn. leaves has yielded three novel biapigenin di-C- glucosides, i.e., 6,6aEuro(3)-di-C-beta-glucopyranosyl-methylene-(8,8aEuro(3))biapigenin (7), 3,6aEuro(3)-di-C-beta-glucopyranosyl-methylene-(6,8aEuro(3))-biapigenin (8), and 6,6aEuro(3)-di- C-beta-glucopyranosyl-methylene-(3,8aEuro(3))-biapigenin (9), named jatrophenols I-III. In addition, seven known polyphenolic metabolites were identified as apigenin 7-O-beta- neohespredoside (1), ferulic acid (2), quercetrin (3), vicinin-II (4), isoorientin (5), vitexin (6), and luteolin (10) for the first time from this species. The AME of the plant was reported for the first time to have significant analgesic, anti-inflammatory, and antihypertensive effects. |
| Doi | 10.1007/s10600-012-0377-z |
| Wosid | WOS:000312061300010 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000312061300010 |
| Is Public | Yes |
| Keyword | Jatropha multifida; HR-ESI-MS; biapigenin di-C-glucoside; analgesic; anti-inflammatory; antihypertensive |