Experimental poisoning by extracts and fractions of Astragalus lusitanicus Lam. in sheep
Bel-Kassaoui, H; Lamnaouer, D; Abdennebi, EH; Jossang, A
| HERO ID | 1461685 |
|---|---|
| In Press | No |
| Year | 2007 |
| Title | Experimental poisoning by extracts and fractions of Astragalus lusitanicus Lam. in sheep |
| Authors | Bel-Kassaoui, H; Lamnaouer, D; Abdennebi, EH; Jossang, A |
| Journal | Revue de Medecine Veterinaire |
| Volume | 158 |
| Issue | 6 |
| Page Numbers | 269-273 |
| Abstract | The phytochemical study of Astragalus lusitanicus conducted in parallel to the toxicity assays in lambs has shown that the extracts with organic solvents (petroleum ether, ether, ethyl acetate and 1-butanol) are not toxic. In the contrary, the aqueous extract as well as the decoction is toxic. While the lethal dose of the fresh plant is about 30 g/kg body weight (BW), the lethal dose of the decoction is only 1.5 g/kg BW. The fractionation of the decoction allowed to obtain a fraction more concentrated in the toxic principle and was lethal at the dose of aroximately 40 mg /kg only. |
| Wosid | WOS:000248342900001 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000248342900001 |
| Is Public | Yes |
| Language Text | French |
| Keyword | Astragalus lusitanicus Lam; sheep; experimental intoxication; toxic principle |