Effect of dietary monosodium glutamate and cholesterol on growth and lipid metabolism in the rat
Anderson, TA; Redlin, J
| HERO ID | 1483199 |
|---|---|
| In Press | No |
| Year | 1973 |
| Title | Effect of dietary monosodium glutamate and cholesterol on growth and lipid metabolism in the rat |
| Authors | Anderson, TA; Redlin, J |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 143 |
| Issue | 1 |
| Page Numbers | 270-274 |
| Abstract | HEEP COPYRIGHT: BIOL ABS. Male weanling rats were divided into 4 isonitrogenous dietary treatment groups, all of the dietary N and glutamic acid in groups A and B being derived from casein whereas 20% of the N and 65% of the glutamic acid in diets C and D were derived from monosodium glutamate (MSG). Diets B and D contained 1% cholesterol. At the end of a 28 day feeding period, the rats receiving MSG (groups C and D) exhibited the following statistically significant differences from the rats receiving N only from casein (groups A and B): depressed weight gain, heavier kidneys, higher levels of serum albumin, lower levels of serum globulin and a greater percent incorporation of an i.p. injection of 14-C acetate into hepatic 2-p-toluidinyl naphthalene-6-sulfonate (TNS) lipids. Rats fed the diets containing 1% cholesterol (groups B and D) exhibited the following statistically significant differences from those fed the cholestero-free diets (groups A and C): heavier livers, higher levels of serum albumin, globulin and total protein, greater concentration of hepatic cholesterol and lower percent incorporation of an i.p. injection of 14-C acetate into hepatic cholesterol. |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |