To the genotoxicity of stack gas condensates of Bavarian waste incineration plants: III. Emission monitoring with a simple UDS assay using the human lung cell lines NCI-H 322 and 358
Raabe, F; Wichmann, G; Dautzenberg, D; Lierse, C; Zluticky, J; Metzner, G; Muecke, W
| HERO ID | 1483254 |
|---|---|
| In Press | No |
| Year | 1999 |
| Title | To the genotoxicity of stack gas condensates of Bavarian waste incineration plants: III. Emission monitoring with a simple UDS assay using the human lung cell lines NCI-H 322 and 358 |
| Authors | Raabe, F; Wichmann, G; Dautzenberg, D; Lierse, C; Zluticky, J; Metzner, G; Muecke, W |
| Journal | Zentralblatt für Hygiene und Umweltmedizin |
| Volume | 201 |
| Issue | 6 |
| Page Numbers | 513-530 |
| Abstract | BIOSIS COPYRIGHT: BIOL ABS. For the validation of the genotoxicity testing on stack gas condensates from waste incineration plants using bacterial short time tests (15), a modified UDS assay with the lung cell lines NCI-H 322 and 358 was developed. The UDS assay is more sensitive than the SOS chromotest and discriminates better between the negative or weakly positive and the clearly positive samples. It has a high sensitivity and specificity and also accuracy, is practicable in a comparatively simple, speedy and reasonably he two test cell lines. From three plants examined continuously in this period only two emitted stack gases with constantly low genotoxicity at the end of sampling. 5 clean gas condensates, that were taken in random samples from 3 other plants in the period 1994 to 1995, proved to be non-genotoxic in the UDS assay. However, one of these plants emitted stack gases with high cytotoxicity, which might have masked UDS-inducing single substances. It is not possible to make a statement |
| Is Certified Translation | No |
| Dupe Override | 1483254 |
| Is Public | Yes |
| Language Text | ger |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>Public Health: Environmental Health-Air</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Hominidae</kw> |