Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells
Hagopian HK, Riggs MG, Swartz LA, Ingram VM.
HERO ID
1506809
Reference Type
Journal Article
Year
1977
Language
English
PMID
| HERO ID | 1506809 |
|---|---|
| In Press | No |
| Year | 1977 |
| Title | Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells |
| Authors | Hagopian HK, Riggs MG, Swartz LA, Ingram VM. |
| Journal | Cell |
| Volume | 12 |
| Issue | 3 |
| Page Numbers | 855-860 |
| Abstract | n-Butyrate in low concentrations stops reversibly the proliferation of chick embryonic fibroblasts and of HeLa cells, shutting off DNA synthesis. Extensive acetylation of histones is seen at the same time as inhibition of DNA synthesis. Nuclei from n-butyrate-treated HeLa cells remain inactive in control cytosol; control nuclei are strongly inhibited by cytosol from treated cells. |
| Doi | 10.1016/0092-8674(77)90284-7 |
| Pmid | 562721 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |