Ambient Diode Laser Desorption Dielectric Barrier Discharge Ionization Mass Spectrometry of non-volatile chemicals
Gilbert-López, B; Schilling, M; Ahlmann, N; Michels, A; Hayen, H; Molina-Díaz, A; Garcia-Reyes, JF; Franzke, J
| HERO ID | 1506877 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | Ambient Diode Laser Desorption Dielectric Barrier Discharge Ionization Mass Spectrometry of non-volatile chemicals |
| Authors | Gilbert-López, B; Schilling, M; Ahlmann, N; Michels, A; Hayen, H; Molina-Díaz, A; Garcia-Reyes, JF; Franzke, J |
| Journal | Analytical Chemistry |
| Volume | 85 |
| Issue | 6 |
| Page Numbers | 3174-3182 |
| Abstract | In this work, the combined use of desorption by a continuous wave near infrared diode laser and ionization by a dielectric barrier discharge-based probe (laser desorption dielectric barrier discharge ionization mass spectrometry (LD-DBDI-MS)) is presented as an ambient ionization method for the mass spectrometric detection of non-volatile chemicals on surfaces. A separation of desorption and ionization processes could be verified. The use of the diode laser is motivated by its low cost, the ease of use and the small size. To achieve an efficient desorption the glass substrates are coated at the back side with a black point (target point, where the sample is deposited) in order to absorb the energy offered by the diode laser radiation. Subsequent ionization is accomplished by a helium plasmajet generated in the dielectric barrier discharge source. Examples on the application of this approach are shown in both positive and negative ionization modes. A wide variety of multiclass species with low vapor pressure were tested including pesticides, pharmaceuticals and explosives (reserpine, roxithromycin, propazine, prochloraz, spinosad, ampicillin, dicloxacillin, enrofloxacin, tetracycline, oxytetracycline, erythromycin, spinosad, HMX and RDX). A comparative evaluation revealed that the use of the laser is advantageous compared to just heating the substrate surface. |
| Doi | 10.1021/ac303452w |
| Pmid | 23419061 |
| Wosid | WOS:000316520500020 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875465367&doi=10.1021%2fac303452w&partnerID=40&md5=c86ed36a76b999137ffa395a726814b0 |
| Is Public | Yes |
| Language Text | English |