Spontaneous abortions in female populations occupationally exposed to ionizing radiation
Fucic, A; Merlo, DF; Ceppi, M; Lucas, J
HERO ID
1510474
Reference Type
Journal Article
Year
2008
Language
English
PMID
| HERO ID | 1510474 |
|---|---|
| In Press | No |
| Year | 2008 |
| Title | Spontaneous abortions in female populations occupationally exposed to ionizing radiation |
| Authors | Fucic, A; Merlo, DF; Ceppi, M; Lucas, J |
| Journal | International Archives of Occupational and Environmental Health |
| Volume | 81 |
| Issue | 7 |
| Page Numbers | 873-879 |
| Abstract | Objective: Exposure to radioisotopes of metals and halogen elements occurring in medical practice may cause spontaneous abortions. The potential role of occupational exposure to X-rays and internal radioisotopes on pregnancy outcome in childbearing age women employed in hospital departments were analyzed in order to estimate miscarriage risk. Methods: Over a period of 16 years, the occurrence of miscarriages in 61 women exposed to radioisotopes was compared to that reported in 170 X-ray exposed women. Chromosomal aberrations (CA) were measured in both radiation-exposed groups and in 53 non-exposed women. Results: Women exposed to radioisotopes experienced at least a threefold higher rate of spontaneous abortions than those exposed to X-ray (OR = 3.68, 95% CI = 1.39-9.74, P < 0.01). Although X-ray and radioisotopes exposed women had significantly higher levels of chromosome type frequency (0.51 +/- 0.82, and 0.63 +/- 0.99, respectively) than referents (0.17 +/- 0.34), there was no clear difference between radiation-exposed women. Conclusions: For exposure levels within standard recommended guidelines, radioisotopes are far more likely to play a role in the occurrence of spontaneous abortions than X-rays. Such biological effect is not detectable by deviations in CA frequency. |
| Doi | 10.1007/s00420-007-0281-1 |
| Pmid | 18058121 |
| Wosid | WOS:000255113400010 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
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