Effect of race on fine particle deposition for oral and nasal breathing

Bennett, WD; Zeman, KL

HERO ID

155687

Reference Type

Journal Article

Year

2005

Language

English

PMID

16087570

HERO ID 155687
In Press No
Year 2005
Title Effect of race on fine particle deposition for oral and nasal breathing
Authors Bennett, WD; Zeman, KL
Journal Inhalation Toxicology
Volume 17
Issue 12
Page Numbers 641-648
Abstract Nasal efficiency for removing fine particles from inhaled air may be affected by variations in nasal structure associated with race. In 11 African American and 11 Caucasian adults (age 18-31 yr) we measured the fractionaldeposition (DF) of fine particles (1 and 2 μm mass median aerodynamic diameter) (MMAD) for oral and nasal breathing using individual breathing patterns previously measured by respiratory inductance plethysmography during a graded exercise protocol. DF for both nasal and mouth breathing was measured separately by laser photometry at the same tidal volume and breathing rate for resting and light exercise (20% of maximum work load) conditions. From these DF measures, nasal deposition efficiency (NDE) was calculated for each condition. For light exercise conditions, NDE for both 1- and 2-μm particles was less in African Americans versus Caucasians, 0.15 ′ 0.07 (SD) versus 0.24 ′ 0.11 for 1-μm particles (p =.03), and 0.29 ′ 0.13 versus 0.44 ′ 0.11 for 2-μm particles (p = .006). The racial differences in NDE were associated with racial differences in nasal resistance and nostril shape. These race-dependent nasal efficiencies are dosimetric factors that should be considered in modeling and assessing particulate dose from human exposure to air pollutants.
Doi 10.1080/08958370500188984
Pmid 16087570
Wosid WOS:000231082600001
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Is Peer Review Yes