Comedogenicity in rabbit: some cosmetic ingredients/vehicles
Nguyen, SH; Dang, TP; Maibach, HI
HERO ID
1616835
Reference Type
Journal Article
Year
2007
Reference is
Locked
Language
English
PMID
| HERO ID | 1616835 |
|---|---|
| In Press | No |
| Year | 2007 |
| Title | Comedogenicity in rabbit: some cosmetic ingredients/vehicles |
| Authors | Nguyen, SH; Dang, TP; Maibach, HI |
| Journal | Cutaneous and Ocular Toxicology |
| Volume | 26 |
| Issue | 4 |
| Page Numbers | 287-292 |
| Abstract | The rabbit external ear canal was used to define which chemicals caused comedone formation on topical application. Some of the tested ingredients are currently used in topically applied formulations. Certain raw materials have been shown to produce follicular hyperkeratosis in the rabbit ear assay. This study quantifies comedogenic potential of cosmetic materials, including: isopropyl palmitate, isopropyl myristate, butyl stearate, isopropyl isostearate, decyl oleate, isostearyl neopentanoate, isocetyl stearate, myristle myristate, cocoa butter, cetyl alcohol, paraffin, stearyl alcohol sodium lauryl sulfate (SLS), and petrolatum. The first nine were deemed positive. Factors aiding clinical relevance are listed. |
| Doi | 10.1080/15569520701555383 |
| Pmid | 18058303 |
| Wosid | WOS:000251751000002 |
| Is Certified Translation | No |
| Dupe Override | Yes |
| Is Public | Yes |
| Language Text | English |
| Is Qa | Yes |
| Relationship(s) |
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