Some biochemical effects of isopropyl myristate and squalane on rabbit skin

Komatsu, H; Asaba, K; Suzuki, M

HERO ID

1619553

Reference Type

Journal Article

Year

1979

Language

English

HERO ID 1619553
In Press No
Year 1979
Title Some biochemical effects of isopropyl myristate and squalane on rabbit skin
Authors Komatsu, H; Asaba, K; Suzuki, M
Journal Journal of the Society of Cosmetic Chemists
Volume 30
Issue 5
Page Numbers 263-278
Abstract A biochemical method was employed to study the response of rabbit skin to isopropyl myristate, squalane, and decane. The results showed that decane damaged the skin so severely that the biosyntheses of lipids, RNA and DNA were reduced markedly for the first 3 days after application, but increased rapidly after that due to the repair. The effect of squalane was found to be weaker than that of isopropyl myristate, though both oils induced the stimulation of biosynthese in the epidermis. The magnitude of the biochemical effects of the 3 oils on the skin was increased in the order of squalane, isopropyl myristate and decane, which was consistent with the results of macroscopic and histological observations. From the profiles of the effects, it is postulated that the repairing processes are controlled by some feedback mechanisms.
Wosid WOS:A1979HR60900002
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
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