A rationale for lowering the blood lead action level from 10 to 2 μg/dL

Gilbert, SG; Weiss, B

HERO ID

174259

Reference Type

Journal Article

Subtype

Review

Year

2006

Language

English

PMID

16889836

HERO ID 174259
Material Type Review
In Press No
Year 2006
Title A rationale for lowering the blood lead action level from 10 to 2 μg/dL
Authors Gilbert, SG; Weiss, B
Journal NeuroToxicology
Volume 27
Issue 5
Page Numbers 693-701
Abstract Fifteen years ago, in 1991, the U.S. Centers for Disease Control and Prevention (CDC) established 10 microg/dL as the lowest level of concern for children's blood lead levels. This value is extremely important because, historically, policy makers and public health officials generally have acted to remove sources of lead exposure only after the CDC's level of concern had been exceeded. A growing body of evidence, however, reveals that blood lead levels below 10 microg/dL may impair neurobehavioral development. There is now sufficient and compelling scientific evidence for the CDC to lower the blood lead action level in children. This review argues that a level of 2 microg/dL is a useful and feasible replacement. Although it can be argued, in turn, that no threshold for the health effects of lead is demonstrable, analytically a blood level of 2 microg/dL is readily and accurately measured and provides a benchmark for successful prevention. Lowering the level of concern would encourage and accelerate the investments needed to ensure that children are protected from lead exposure in their homes, schools, and play settings. Such a program would also offer economic advantages because of the coupling between lead, educational attainment, earnings and anti-social conduct. By lowering the blood action level, CDC will promote policies and initiatives designed to further reduce children's exposure to this potent developmental neurotoxicant.
Doi 10.1016/j.neuro.2006.06.008
Pmid 16889836
Wosid WOS:000240408800006
Is Certified Translation No
Dupe Override No
Conference Location Research Triangle Park, NC
Conference Name 22nd International Neurotoxicology Conference
Comments Alternate WOS ID: BCI:BCI200700091662
Is Public Yes
Language Text English
Keyword Lead; Children; Ethics; CDC; Regulation; Earnings; Assays
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