Ceruloplasmin, copper, selenium, iron, zinc, and manganese levels in normal and sulfite oxidase deficient rat plasma: Effects of sulfite exposure

Herken, E; Kocamaz, E; Kucukatay, M; Vural, H; Demirin, H; Kucukatay, V

HERO ID

1753443

Reference Type

Journal Article

Year

2008

Language

English

PMID

18286237

HERO ID 1753443
In Press No
Year 2008
Title Ceruloplasmin, copper, selenium, iron, zinc, and manganese levels in normal and sulfite oxidase deficient rat plasma: Effects of sulfite exposure
Authors Herken, E; Kocamaz, E; Kucukatay, M; Vural, H; Demirin, H; Kucukatay, V
Journal Biological Trace Element Research
Volume 123
Issue 1-3
Page Numbers 202-210
Abstract A noticeable effect of sulfite treatment was observed on the plasma ceruloplasmin ferroxidase activity of rats with normal sulfite oxidase activity when compared to normal controls. The plasma levels of selenium, iron, and zinc were unaffected by sulfite in normal and sulfite oxidase (SOX)-deficient rats. While plasma level of Mn was decreasing, plasma Cu level increased in SOX-deficient rats. Treating SOX-deficient groups with sulfite did not alter plasma level of Mn but made plasma level of Cu back to its normal level. This is the first evidence that Cu and Mn status were affected in experimental sulfite oxidase deficiency induced by low molybdenum diet with tungsten addition deserving further research to determine the underlying mechanisms of these observations in experimental sulfite oxidase deficiency.
Doi 10.1007/s12011-008-8105-z
Pmid 18286237
Wosid WOS:000256084000023
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000256084000023
Is Public Yes
Language Text English
Keyword sulfite oxidase; sulfite; ceruloplasmin; copper; selenium; iron; zinc; manganese; rat plasma