Mutagenic activity in roadside soils

Tsukatani, H; Tanaka, Y; Sera, N; Shimizu, N; Kitamori, S; Inoue, N

HERO ID

180021

Reference Type

Journal Article

Year

2002

Language

English

PMID

12238142

HERO ID 180021
In Press No
Year 2002
Title Mutagenic activity in roadside soils
Authors Tsukatani, H; Tanaka, Y; Sera, N; Shimizu, N; Kitamori, S; Inoue, N
Journal Journal of Toxicological Sciences
Volume 27
Issue 3
Page Numbers 183-189
Abstract Mutagenicity of soils sampled at median strips, roadsides and a park neighboring arterial roads in Kurume City was determined by Ames test. Organic extracts of soils were mutagenic in strains TA98, TA100, YG1041 and YG1042 with and without S9mix. No sample showed mutagenic responses in strains YG3003 or YG7108. Extracts from soils of median strips and beside intersections showed higher mutagenicity and concentrations of PAHs and heavy metals than others, and mutagenic activity of soils correlated significantly with concentrations of PAHs and heavy metals. However, PAHs accounted for less than 12% of total mutagenicity in strains TA98 and TA100 of soil extracts. These extracts showed much higher mutagenicity in YG strains than in TA strains. The results indicate that these soils may be polluted with nitroarenes and aromatic amines.
Doi 10.2131/jts.27.183
Pmid 12238142
Url http://www.jstage.jst.go.jp/article/jts/27/3/27_3_183/_article
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Ames test; Mutagenicity; Polycyclic aromatic hydrocarbons; Soil
Is Qa No