Comparison of x-ray films and low-dose computed tomographic scans: demonstration of asbestos-related changes in 2760 nuclear weapons workers screened for lung cancer

Miller, A; Widman, SA; Miller, JA; Manowitz, A; Markowitz, SB

HERO ID

1807989

Reference Type

Journal Article

Year

2013

Language

English

PMID

23787562

HERO ID 1807989
In Press No
Year 2013
Title Comparison of x-ray films and low-dose computed tomographic scans: demonstration of asbestos-related changes in 2760 nuclear weapons workers screened for lung cancer
Authors Miller, A; Widman, SA; Miller, JA; Manowitz, A; Markowitz, SB
Journal Journal of Occupational and Environmental Medicine
Volume 55
Issue 7
Page Numbers 741-745
Abstract <strong>OBJECTIVE: </strong>Increased availability and technical improvements of computed tomographic (CT) scanning encourages its use for detecting asbestos-related disease. We compared low-dose scans and x-ray films in 2760 workers potentially exposed to asbestos, to assess their ability to detect interstitial lung disease (ILD) and pleural thickening (PT).<br /><br /><strong>METHODS: </strong>A total of 2760 nuclear workers received radiography and CT scanning (2006 to 2009). X-ray films were read by a B reader for ILD and PT and CT scans by a thoracic radiologist, using a protocol for nodules, ILD, and PT.<br /><br /><strong>RESULTS: </strong>Of the 2760 workers, 271 showed circumscribed PT on CT scans, and 73 on x-ray films, 54 (74%) of which were confirmed on CT scans; 76 showed ILD on CT scans, and 15 on x-ray film, 10 (67%) of which were confirmed on CT scans.<br /><br /><strong>CONCLUSIONS: </strong>Radiographic readings of PT and ILD were generally confirmed on CT scans. Computed tomographic scans detected three to five times more cases; the majority were minor.
Doi 10.1097/JOM.0b013e3182954067
Pmid 23787562
Wosid WOS:000330447900004
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Occupational Health And Safety; Radiography; Tomography; Nuclear weapons; Lung cancer; Comparative analysis; Medical screening