Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO2(mpETSC)] and [Pt(mpETSC)Cl]
Elsayed, SA; El-Hendawy, AM; Mostafa, SI; Jean-Claude, BJ; Todorova, M; Butler, I
HERO ID
1840001
Reference Type
Journal Article
Year
2010
Language
English
PMID
| HERO ID | 1840001 |
|---|---|
| In Press | No |
| Year | 2010 |
| Title | Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO2(mpETSC)] and [Pt(mpETSC)Cl] |
| Authors | Elsayed, SA; El-Hendawy, AM; Mostafa, SI; Jean-Claude, BJ; Todorova, M; Butler, I |
| Journal | Bioinorganic Chemistry and Applications |
| Page Numbers | 149149 |
| Abstract | New complexes of dioxovanadium(V), zinc(II), ruthenium(II), palladium(II), and platinum(II) with 6-methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone (HmpETSC) have been synthesized. The composition of these complexes is discussed on the basis of elemental analyses, IR, Raman, NMR ((1)H, (13)C, and (31)P), and electronic spectral data. The X-ray crystal structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl] are also reported. The HmpETSC and its [Zn(HmpETSC)Cl(2)] and [Pd(mpETSC)Cl] complexes exhibit antineoplastic activity against colon cancer human cell lines (HCT 116). |
| Doi | 10.1155/2010/149149 |
| Pmid | 20671978 |
| Wosid | WOS:000280795400001 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000280795400001 |
| Is Public | Yes |
| Language Text | English |