Do levels of airborne grass pollen influence asthma hospital admissions?

Erbas, B; Chang, JH; Dharmage, S; Ong, EK; Hyndman, R; Newbigin, E; Abramson, M

HERO ID

186919

Reference Type

Journal Article

Year

2007

Language

English

PMID

17877763

HERO ID 186919
In Press No
Year 2007
Title Do levels of airborne grass pollen influence asthma hospital admissions?
Authors Erbas, B; Chang, JH; Dharmage, S; Ong, EK; Hyndman, R; Newbigin, E; Abramson, M
Journal Clinical and Experimental Allergy
Volume 37
Issue 11
Page Numbers 1641-1647
Abstract BACKGROUND: The effects of environmental factors and ambient concentrations of grass pollen on allergic asthma are yet to be established. OBJECTIVE: We sought to estimate the independent effects of grass pollen concentrations in the air over Melbourne on asthma hospital admissions for the 1992-1993 pollen season. METHODS: Daily grass pollen concentrations were monitored over a 24-h period at three stations in Melbourne. The outcome variable was defined as all-age asthma hospital admissions with ICD9-493 codes. The ambient air pollutants were average daily measures of ozone, nitrogen dioxide and sulphur dioxide, and the airborne particle index representing fine particulate pollution. Semi-parametric Poisson regression models were used to estimate these effects, adjusted for air temperature, humidity, wind speed, rainfall, day-of-the-week effects and seasonal variation. RESULTS: Grass pollen was a strong independent non-linear predictor of asthma hospital admissions in a multi-pollutant model (P=0.01). Our data suggest that grass pollen had an increasing effect on asthma hospital admissions up to a threshold of 30 grains/m3, and that the effect remains stable thereafter. CONCLUSION: Our findings suggest that grass pollen levels influence asthma hospital admissions. High grass pollen days, currently defined as more than 50 grains/m3, are days when most sensitive individuals will experience allergic symptoms. However, some asthmatic patients may be at a significant risk even when airborne grass pollen levels are below this level. Patients with pollen allergies and asthma would be advised to take additional preventive medication at lower ambient concentrations.
Doi 10.1111/j.1365-2222.2007.02818.x
Pmid 17877763
Wosid WOS:000250252200009
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword air pollution; ambient pollen; asthma; non-linearity; statistical models
Is Qa No
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