Vanadium nitrogenase: A two-hit wonder?
Hu, Y; Lee, ChiC; Ribbe, MW
HERO ID
2036275
Reference Type
Journal Article
Subtype
Review
Year
2012
Language
English
PMID
| HERO ID | 2036275 |
|---|---|
| Material Type | Review |
| In Press | No |
| Year | 2012 |
| Title | Vanadium nitrogenase: A two-hit wonder? |
| Authors | Hu, Y; Lee, ChiC; Ribbe, MW |
| Journal | Dalton Transactions |
| Volume | 41 |
| Issue | 4 |
| Page Numbers | 1118-1127 |
| Abstract | Nitrogenase catalyzes the biological conversion of atmospheric dinitrogen to bioavailable ammonia. The molybdenum (Mo)- and vanadium (V)-dependent nitrogenases are two homologous members of this metalloenzyme family. However, despite their similarities in structure and function, the characterization of V-nitrogenase has taken a much longer and more winding path than that of its Mo-counterpart. From the initial discovery of this nitrogen-fixing system, to the recent finding of its CO-reducing capacity, V-nitrogenase has proven to be a two-hit wonder in the over-a-century-long research of nitrogen fixation. This perspective provides a brief account of the catalytic function and structural basis of V-nitrogenase, as well as a short discussion of the theoretical and practical potentials of this unique metalloenzyme. |
| Doi | 10.1039/c1dt11535a |
| Pmid | 22101422 |
| Wosid | WOS:000299054200002 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |