Asbestos-induced visceral pleural fibrosis reduces pulmonary compliance
Valkila, EH; Nieminen, MM; Moilanen, AK; Kuusisto, PA; Lahdensuo, AH; Karvonen, JI
HERO ID
2079031
Reference Type
Journal Article
Year
1995
Language
English
PMID
| HERO ID | 2079031 |
|---|---|
| In Press | No |
| Year | 1995 |
| Title | Asbestos-induced visceral pleural fibrosis reduces pulmonary compliance |
| Authors | Valkila, EH; Nieminen, MM; Moilanen, AK; Kuusisto, PA; Lahdensuo, AH; Karvonen, JI |
| Journal | American Journal of Industrial Medicine |
| Volume | 28 |
| Issue | 3 |
| Page Numbers | 363-372 |
| Abstract | To determine the nature of respiratory functional impairment caused by asbestos-induced visceral pleural fibrosis (VPF) and to discover which pulmonary physiological variable best reveals it, we examined 59 asbestos-exposed construction workers having asbestos-related changes on chest radiographs. Computed tomography scans of the thorax were also performed. Visceral pleural fibrosis was diagnosed in 29 subjects: seven had only VPF, 17 had VPF and pleural plaques, and five had VPF, plaques, and asbestosis. In subjects without VPF, 23 had plaques, six had plaques and asbestosis, and one had only minor fibrotic parenchymal changes insufficient for a diagnosis of asbestosis. Flow-volume spirometry, body plethysmography, static and dynamic compliance, and pulmonary diffusing capacity for carbon monoxide were measured. The subjects with VPF had significantly lower static (p = 0.005) and dynamic (p = 0.007) compliance values than those without. Other respiratory function variables failed to show any significant differences. We conclude that the measurement of static and dynamic compliance is a useful method in assessing pulmonary function impairment caused by visceral pleural fibrosis. |
| Doi | 10.1002/ajim.4700280306 |
| Pmid | 7485190 |
| Wosid | WOS:A1995RQ05000005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | asbestos; computed tomography of thorax; construction workers; diffuse pleural thickening; occupational health; pulmonary compliance; pulmonary function; visceral pleural fibrosis |