The pivotal role of pathology in the management of lung cancer

Davidson, MR; Gazdar, AF; Clarke, BE

HERO ID

2218105

Reference Type

Journal Article

Subtype

Review

Year

2013

Language

English

PMID

24163740

HERO ID 2218105
Material Type Review
In Press No
Year 2013
Title The pivotal role of pathology in the management of lung cancer
Authors Davidson, MR; Gazdar, AF; Clarke, BE
Journal Journal of Thoracic Disease
Volume 5
Issue Suppl 5
Page Numbers S463-S478
Abstract The last decade has seen significant advances in our understanding of lung cancer biology and management. Identification of key driver events in lung carcinogenesis has contributed to the development of targeted lung cancer therapies, heralding the era of personalised medicine for lung cancer. As a result, histological subtyping and molecular testing has become of paramount importance, placing increasing demands on often small diagnostic specimens. This has triggered the review and development of the first structured classification of lung cancer in small biopsy/cytology specimens and a new classification of lung adenocarcinoma from the IASLC/ATS/ERS. These have enhanced the clinical relevance of pathological diagnosis, and emphasise the role of the modern surgical pathologist as an integral member of the multidisciplinary team, playing a crucial role in clinical trials and determining appropriate and timely management for patients with lung cancer.
Doi 10.3978/j.issn.2072-1439.2013.08.43
Pmid 24163740
Is Certified Translation No
Dupe Override No
Comments Journal: Journal of thoracic disease ISSN: 2072-1439
Is Public Yes
Language Text English