Dietary exposure to perfluoroalkyl acids of specific French adult sub-populations: High seafood consumers, high freshwater fish consumers and pregnant women
Yamada, A; Bemrah, N; Veyrand, B; Pollono, C; Merlo, M; Desvignes, V; Sirot, V; Marchand, P; Berrebi, A; Cariou, R; Antignac, JP; Le Bizec, B; Leblanc, JC
HERO ID
2324905
Reference Type
Journal Article
Year
2014
Language
English
PMID
| HERO ID | 2324905 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | Dietary exposure to perfluoroalkyl acids of specific French adult sub-populations: High seafood consumers, high freshwater fish consumers and pregnant women |
| Authors | Yamada, A; Bemrah, N; Veyrand, B; Pollono, C; Merlo, M; Desvignes, V; Sirot, V; Marchand, P; Berrebi, A; Cariou, R; Antignac, JP; Le Bizec, B; Leblanc, JC |
| Journal | Science of the Total Environment |
| Volume | 491-492 |
| Issue | Elsevier |
| Page Numbers | 170-175 |
| Abstract | Perfluoroalkyl acids (PFAAs) are globally found in various media, including food and especially fishery products. In the present study, the dietary exposure to 15 perfluoroalkyl acids was assessed for 3 French adult populations, namely high seafood consumers, high freshwater fish consumers, and pregnant women. Purified food extracts were analysed by LC-MS/MS and PFBA, PFPA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnA, PFTrDA, PFTeDA, PFBS, PFHxS, PFHpS, PFOS and PFDS were monitored and quantified according to the isotope dilution principle. Under lower bound (LB) hypothesis (i.e. contamination values<LOD considered as 0), high freshwater fish consumers appear as the most exposed to PFOS (7.5ng.kg(-1) bw.d(-1)), PFUnA (1.3ng.kg(-1) bw.d(-1)), PFDA (0.4ng.kg(-1) bw.d(-1)) and PFHpS (0.03ng.kg(-1) bw.d(-1)) while high seafood consumers appear as the most exposed to PFOA (1.2ng.kg(-1) bw.d(-1)), PFNA (0.2ng.kg(-1) bw.d(-1)) and PFHxS (0.06ng.kg(-1) bw.d(-1)). For all considered populations, the major exposure contributors are fish, seafood and water under LB hypothesis, while dairy products, bread and crispbread are the main contributors under upper bound (UB) hypothesis. Besides this food exposure assessment, further studies are needed to assess the more global PFAA exposure, taking into account indoor and outdoor air, dust and cutaneous contact, which could be other important contributors for this particular class of chemicals. |
| Doi | 10.1016/j.scitotenv.2014.01.089 |
| Pmid | 24530183 |
| Wosid | WOS:000339534700023 |
| Url | https://linkinghub.elsevier.com/retrieve/pii/S0048969714001077 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Dietary exposure; Perfluoroalkyl acid; Fish consumer; Pregnant woman |
| Is Peer Review | Yes |
| Relationship(s) |
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