Fabrication of ZIF-8@SiO2 Core-Shell Microspheres as the Stationary Phase for High-Performance Liquid Chromatography
Fu, Y; Yang, CX; Yan, X
| HERO ID | 2400783 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | Fabrication of ZIF-8@SiO2 Core-Shell Microspheres as the Stationary Phase for High-Performance Liquid Chromatography |
| Authors | Fu, Y; Yang, CX; Yan, X |
| Journal | Chemistry: A European Journal |
| Volume | 19 |
| Issue | 40 |
| Page Numbers | 13484-13491 |
| Abstract | The unique features of high porosity, shape selectivity, and multiple active sites make metal-organic frameworks (MOFs) promising as novel stationary phases for high-performance liquid chromatography (HPLC). However, the wide particle size distribution and irregular shape of conventional MOFs lead to lower column efficiency of such MOF-packed columns. Herein, the fabrication of monodisperse MOF@SiO2 core-shell microspheres as the stationary phase for HPLC to overcome the above-mentioned problems is reported. Zeolitic imidazolate framework8 (ZIF-8) was used as an example of MOFs due to its permanent porosity, uniform pore size, and exceptional chemical stability. Unique carboxyl-modified silica spheres were used as the support to grow the ZIF-8 shell. The fabricated monodisperse ZIF-8@SiO2 packed columns (5cm long x 4.6mm i.d.) show high column efficiency (23000platesm(-1) for bisphenolA) for the HPLC separation of endocrine-disrupting chemicals (bisphenolA, -estradiol, and p-(tert-octyl)phenol) and pesticides (thiamethoxam, hexaflumuron, chlorantraniliprole, and pymetrozine) within 7min with good relative standard deviations for 11replicate separations of the analytes (0.01-0.39, 0.65-1.7, 0.70-1.3, and 0.17-0.91% for retention time, peak area, peak height, and half peak width, respectively). The ZIF-8@SiO2 microspheres combine the advantages of the good column packing properties of the uniform monodisperse silica microspheres and the separation ability of the ZIF-8 crystals. |
| Doi | 10.1002/chem.201301461 |
| Pmid | 23955766 |
| Wosid | WOS:000325091300031 |
| Url | https://www.proquest.com/scholarly-journals/fabrication-zif-8-sio2-core-shell-microspheres-as/docview/1437197360/se-2?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | core-shell microspheres; liquid chromatography; metal-organic frameworks; stationary phases; zeolites |