ANALYSIS OF HUMAN EXHALED BREATH IN A POPULATION OF YOUNG VOLUNTEERS

Zaric, B; Petrovic, S; Bjekic, M; Rajic, I; Popovic, A; Dordevic, D

HERO ID

2858152

Reference Type

Journal Article

Year

2014

Language

English

HERO ID 2858152
In Press No
Year 2014
Title ANALYSIS OF HUMAN EXHALED BREATH IN A POPULATION OF YOUNG VOLUNTEERS
Authors Zaric, B; Petrovic, S; Bjekic, M; Rajic, I; Popovic, A; Dordevic, D
Journal Archives of Biological Sciences
Volume 66
Issue 4
Page Numbers 1529-1538
Abstract Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol were found as well. We detected substituted compounds in exhaled breath.
Doi 10.2298/ABS1404529Z
Wosid WOS:000346477900027
Url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921629917&doi=10.2298%2fABS1404529Z&partnerID=40&md5=aec28399a5b480228fa0cf4e0a592443
Is Certified Translation No
Dupe Override No
Comments Journal:ARCHIVES OF BIOLOGICAL SCIENCES 0354-4664
Is Public Yes
Language Text English
Keyword alveolar breath; volatile organic compounds; exhaled breath condensate; gas chromatography