[Guinea-pig closed patch test]
Yoshikawa, H; Tsuyoshi, T; Okamoto, K; Nakamura, K; Ito, K; Imai, H
HERO ID
3041256
Reference Type
Journal Article
Year
1984
Language
Japanese
| HERO ID | 3041256 |
|---|---|
| In Press | No |
| Year | 1984 |
| Title | [Guinea-pig closed patch test] |
| Authors | Yoshikawa, H; Tsuyoshi, T; Okamoto, K; Nakamura, K; Ito, K; Imai, H |
| Journal | Skin Research |
| Volume | 26 |
| Issue | 5 |
| Page Numbers | 1092-1101 |
| Abstract | We performed several test methods for safety evaluation of cosmetic ingredients and products. Now we chose guinea pig closed patch test method. This study were performed in the 3 different laboratories. The test mamterials were propylene glycol, 1, 3-butylene glycol, glycerin, liquid paraffin, squalane, and pristane. We chose 100% propylene glycol and pristane as positive control, and distilled water as negative control. We performed this test with the same procedure in each laboratory. The results of this study were as following: (1) In three polyols, only 100% propylene glycol reacted but 1, 3-butylene glycol and glycerin showed no reactions. (2) In three hydrocarbons, the order of positive rate was pristane<liquid paraffin<squalane. Squalane showed almost all negative reactions. (3) The reactions of polyols diminished in the course of time. But the reactions of hydrocarbons continued for a time. |
| Doi | 10.11340/skinresearch1959.26.1092 |
| Url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007953552&doi=10.11340%2fskinresearch1959.26.1092&partnerID=40&md5=e45e2e667ac82a9aadc062602b6042bc |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | Japanese |