Contact-dermatitis from stearyl alcohol and propylene-glycol in fluocinonide cream
Shore, RN; Shelley, WB
HERO ID
3047256
Reference Type
Journal Article
Year
1974
Language
English
PMID
| HERO ID | 3047256 |
|---|---|
| In Press | No |
| Year | 1974 |
| Title | Contact-dermatitis from stearyl alcohol and propylene-glycol in fluocinonide cream |
| Authors | Shore, RN; Shelley, WB |
| Journal | Archives of Dermatology |
| Volume | 109 |
| Issue | 3 |
| Page Numbers | 397-399 |
| Abstract | A young woman being treated for linear scleroderma became allergic to fluocinonide (Lidex) cream while using it with occlusion. She was able to continue treatment with fluocinonide ointment without an adverse reaction. Patch testing with the ingredients of the cream demonstrated sensitization to an impurity in commercial stearyl alcohol and irritation from propylene glycol. The woman had no adverse reactions to fluocinonide ointment because this preparation contains no stearyl alcohol and very little propylene glycol. This case reemphasizes the important role of vehicles in contact allergy and indicates that allergic sensitization may be induced despite the presence of a potent topical steroid. |
| Doi | 10.1001/archderm.109.3.397 |
| Pmid | 4814942 |
| Wosid | WOS:A1974S426300013 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Is Peer Review | Yes |
| Relationship(s) |