Naphthalene cataracts in rats Association of eye pigmentation and cataract development

Koch, HR; Doldi, K; Hockwin, O

HERO ID

32884

Reference Type

Journal Article

Year

1976

Language

English

HERO ID 32884
In Press No
Year 1976
Title Naphthalene cataracts in rats Association of eye pigmentation and cataract development
Authors Koch, HR; Doldi, K; Hockwin, O
Journal Documenta Ophthalmologica
Volume 48
Page Numbers 293-303
Abstract The development of naphthalene cataracts was studied in 5 strains of rattus norvegicus of different pigmentation. Whereas all animals of the pigmented strains (E3, BDE, DA) developed zonular cataracts after latencies of 20 to 28 days, only some of the albinos (Wistar, Sprague Dawley) exhibited less pronounced changes after longer latencies of 32 to 61 days. The possible importance of the melanin-synthetizing enzyme phenol oxidase (tyrosinase) of the iris for the formation of the cataractogenic substance 1,2-naphthodiquinone is discussed.
Doi 10.1007/978-94-010-1571-4_31
Is Certified Translation No
Dupe Override No
Comments Doc. Ophthalmol. 48: 293-303.
Is Public Yes
Language Text English
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