Validation of self-reported chronic obstructive pulmonary disease in a cohort study of nurses
Barr, RG; Herbstman, J; Speizer, FE; Camargo, CA, Jr
HERO ID
34882
Reference Type
Journal Article
Year
2002
Language
English
PMID
| HERO ID | 34882 |
|---|---|
| In Press | No |
| Year | 2002 |
| Title | Validation of self-reported chronic obstructive pulmonary disease in a cohort study of nurses |
| Authors | Barr, RG; Herbstman, J; Speizer, FE; Camargo, CA, Jr |
| Journal | American Journal of Epidemiology |
| Volume | 155 |
| Issue | 10 |
| Page Numbers | 965-971 |
| Abstract | Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death, and its prevalence is increasing; however, few strategies are available for disease prevention or modification besides smoking interventions. To facilitate examination of modifiable risk factors for COPD in the Nurses' Health Study, the authors validated a questionnaire-based definition of COPD in a subset of this US cohort. Participants were surveyed biennially about lifestyle factors, including smoking, since 1976 and physician diagnosis of COPD since 1988. Self-reported cases were defined as reporting COPD on both the original (1988-1996) and supplemental (1998) questionnaires. The authors requested medical records for a 10% random sample of 2,790 cases and reviewed these records in a systematic, blinded fashion. Validated cases required obstructive spirometry, emphysema on chest radiograph or computed tomography, or physician diagnosis. COPD was confirmed for 78% of 273 cases. Spirometry or radiographic results were available for 84%; when available, mean forced expiratory volume in 1 second was 51% predicted (standard deviation, 19). Applying these results to a hypothetical cohort, the authors estimated the degree to which disease misclassification biases relative risks toward the null value, confirming that questionnaire-based COPD research should focus on minimizing false positives rather than false negatives. In conclusion, COPD can be studied in large, questionnaire-based cohorts of health professionals. |
| Doi | 10.1093/aje/155.10.965 |
| Pmid | 11994237 |
| Wosid | WOS:000175628800012 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ECRIB. |
| Is Public | Yes |
| Language Text | English |